As of my last knowledge update in January 2022, I don't have specific information about a Paula's Choice 25% Vitamin C + Glutathione Clinical Serum. It's possible that this product was released or updated after that date, or it might be a formulation that I'm not aware of.

However, I can provide you with general information about vitamin C and glutathione in skincare products:

1. Vitamin C (Ascorbic Acid):

   • Role: Vitamin C is known for its antioxidant properties and its ability to brighten the skin, reduce hyperpigmentation, and stimulate collagen production.
   • Concentration: Vitamin C serums often come in various concentrations, typically ranging from 5% to 20%.
   • Usage: It's commonly used in the morning as part of a skincare routine, applied before sunscreen.

2. Glutathione:

   • Role: Glutathione is an antioxidant that plays a role in skin health. It can help lighten hyperpigmentation and even out skin tone.
   • Formulations: Glutathione is often included in skincare products or may be taken as a supplement.
   • Usage: Its effectiveness can vary, and some users prefer it for addressing skin discoloration.

If Paula's Choice has released a new product with the specifications you mentioned, it's essential to check the official Paula's Choice website or contact their customer service for the most accurate and up-to-date information. Additionally, you may find user reviews and testimonials to gauge the effectiveness of the product.

Always perform a patch test when incorporating new skincare products, especially those with higher concentrations of active ingredients, to ensure compatibility with your skin and to minimize the risk of irritation. If you have specific skin concerns or conditions, consider consulting with a dermatologist before introducing new products into your skincare routine. 

ingredients, based on general knowledge of skincare formulations. Keep in mind that formulations may vary, and it's always advisable to refer to the product's official details for the most accurate information. Here's a technical breakdown:

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum: Technical Details

1. Ingredients:

   • Vitamin C (Ascorbic Acid):

     • Role: Ascorbic acid is a potent antioxidant known for its ability to neutralize free radicals, brighten the skin, and promote collagen synthesis.
     • Concentration: A 25% concentration of vitamin C suggests a high-potency formula, which can be effective for addressing various skin concerns.

   • Glutathione:

     • Role: Glutathione is an antioxidant that contributes to a more even skin tone by targeting hyperpigmentation and promoting skin brightness.
     • Concentration: The specific concentration of glutathione in the formulation will impact its efficacy and potential benefits.

2. Formulation:

   • Serum Base:

     • Texture: Clinical serums are often formulated to have a lightweight and easily absorbable texture.
     • Vehicle: The serum base may contain water, glycerin, or other hydrating ingredients to ensure the stability and penetration of active components.

   • Stabilizers and Preservatives:

     • To maintain potency: Antioxidants like vitamin C are sensitive to light and air, so stabilizers like tocopherol (vitamin E) or ferulic acid may be included.
     • Preservatives: Ingredients like phenoxyethanol or ethylhexylglycerin may be used to preserve the product.

3. Usage Instructions:

   • Application: Clinical serums are typically applied after cleansing and toning, before heavier creams or moisturizers.
   • Frequency: The recommended frequency may vary, but vitamin C serums are often used in the morning to benefit from their antioxidant properties throughout the day.

4. Packaging:

   • Opaque Packaging: To protect the stability of vitamin C, the serum may be housed in opaque or dark-colored packaging to shield it from light.

5. Skin Benefits:

   • Brightening: The combination of vitamin C and glutathione suggests a focus on brightening the skin and addressing hyperpigmentation.
   • Antioxidant Protection: Users may experience increased protection against environmental stressors due to the antioxidant properties of vitamin C and glutathione.

6. Patch Testing:

   • Recommendation: Users are typically advised to perform a patch test before regular use, especially with high-potency formulations, to check for potential irritation.

7. Precautions:

   • Sun Protection: Products with vitamin C often recommend using sunscreen during the day to enhance sun protection.

Please note that this technical breakdown is a general overview, and specific details about the Paula's Choice 25% Vitamin C + Glutathione Clinical Serum should be obtained from the product's official information, ingredient list, and usage instructions provided by the brand. Always follow the recommended usage guidelines and consult with a dermatologist if you have specific skin concerns or conditions.